These are a few tools that were built for the sole purpose of removing specific pieces of malware.
It should be noted that one should have utilities that repair internet connections such as, WinsockFix, to recover in case the malware damages your internet connection during the removal process.
We will begin with plug-ins for Adaware SE. These are simply add-ons for Ad-aware that extend its functionality.
VX2 Cleaner
Description: This plug-in allows Ad-aware to effectively remove the VX2 Malware.
Know your enemy: VX2 Description
TV Media Removal Tool
Description: This plug-in allows Ad-aware to effectively remove the TV Media Adware.
Know your enemy: TV Media Description
Now that the Ad-aware SE plug-ins have been mentioned, lets move on to stand alone applications.
Kazaa Begone
Description: This removes all the bundled adware applications associated with Kazaa Media Desktop.
Know your enemy: Kazaa
CWSmartKiller Removal Tool
Description: This removes the CWS.Smartkiller Trojan that causes many antispyware applications to crash upon startup.
Know your enemy: See Merijn's Description of this trojan
Kill2Me
Description: This removes the Look2Me Parasite.
Know your enemy: Look2Me Hijacker
About:Buster
Description: This removes the dreaded About:Blank hijack.
Know your enemy: About:blank infections are easy to recognize because the user's homepage is changed to a hijacker's homepage with address in the bar usually About:Blank.
PeperFix
Description: Supposedly removes the Peper Trojan.
Know your enemy: Peper Trojan Description
This concludes this small roundup of mini malware removal tools. I hope it helps :)